Can I Take Nurofen Plus and Paracetamol: Safety Guide

Can I Take Nurofen Plus and Paracetamol: Safety and Dosage Guide

Are you wondering about the safety and effectiveness of combining Nurofen Plus and paracetamol for pain relief? Let’s delve into the details to help you make informed decisions about managing your pain. Understanding how these medications work together is crucial for your well-being.

So, let’s explore the potential risks and benefits of taking Nurofen Plus and paracetamol simultaneously.

Types of Common Pain Medications

  • Ibuprofen: Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), reduces hormones that cause pain and swelling. Effective for headaches, migraines, back pain, period pain, toothache, and arthritis.
  • Codeine: An opiate, codeine blocks pain signals in the central nervous system and brain, reducing anxiety from pain. Use with caution due to potential addiction.
  • Paracetamol (Acetaminophen): Works by blocking enzymes that produce pain-related prostaglandins.

    Commonly used for pain relief and fever reduction, interacts with the endocannabinoid system to inhibit pain perception.

Each medication has its benefits and side effects. Always consult a healthcare professional before starting a new pain management regimen. ๐ŸŒŸ

Understanding Nurofen Plus and Paracetamol

IMG Source: chemistdirect.co.uk

Potential Risks of Combining Nurofen Plus and Paracetamol

Potential Risks of Combining Nurofen Plus and Paracetamol

  • Safety of Combining Nurofen (Ibuprofen) and Paracetamol:
    • Nurofen (ibuprofen) and paracetamol are commonly used for pain relief but work through distinct mechanisms. Fortunately, when taken together, they do not significantly interact harmfully. However, it’s crucial to adhere to recommended dosages.
  • Clinical Evidence and Therapeutic Rationale:
    • Combining paracetamol with an NSAID like ibuprofen may provide better pain relief than either drug alone.

      NSAIDs, including ibuprofen, have various effects by inhibiting prostaglandins.

    • Precautions and Side Effects:
      • Both NSAIDs and paracetamol can have side effects, such as liver damage from paracetamol and gut problems or kidney issues from ibuprofen, especially in those with other health conditions.
  • Recommendations:
    • Consider non-pharmacological methods or just paracetamol for mild pain.
    • For short-term moderate pain relief, paracetamol/ibuprofen combinations could be an alternative to codeine-based options. However, these combinations are not suitable for chronic pain management.

Always consult with a healthcare professional before combining medications, particularly if you have underlying health issues or are on other drugs. Prioritize safety first!


A blister pack of white pills with four pills pushed out of the packaging.

IMG Source: nps.org.au

Safety Guidelines for Painkillers

  • Safety Precautions and Dosage Guidelines
  • Nurofen Plus (Codeine/Ibuprofen):
    • Nurofen Plus is a combination painkiller containing both codeine (an opioid) and ibuprofen (a non-steroidal anti-inflammatory drug or NSAID).
    • Dosage: It should be used at the lowest effective dose for the shortest period of time. The maximum daily dose should not exceed 6 tablets in 24 hours.
    • Duration: The treatment duration should be limited to 3 days. If effective pain relief is not achieved within this time, consult a doctor.
    • Precautions:
      • Avoid Nurofen Plus if you are allergic to other NSAIDs or have a stomach ulcer.
      • People with heart failure, liver disease, kidney problems, or systemic lupus erythematosus (SLE) should be cautious and consult a doctor.
      • Pregnant women should consult their doctor, and paracetamol is generally safer during pregnancy.
      • Avoid Nurofen completely in the third trimester of pregnancy, as it can affect the babyโ€™s heart.
  • Paracetamol:
    • Paracetamol is commonly used to treat pain and reduce fever.
    • Dosage: It has few side effects, and most people can take it.

      The recommended maximum dose is 4000 mg in a 24-hour period.

    • Precautions:
      • Consult your doctor if you have liver or kidney problems.
      • Pregnant women can safely take paracetamol, but always consult a doctor during pregnancy.
  • Taking Both Together:
    • Paracetamol and anti-inflammatory drugs like Nurofen are different, so itโ€™s safe to take them together, either at the same time or spaced apart.
    • Ibuprofen is best taken with food or on a full stomach.
    • Always follow the instructions on the label or leaflet to avoid exceeding the recommended amount of each medicine.

Remember that proper dosing and understanding potential interactions are crucial for your safety. If you have any concerns, consult a healthcare professional.

A leaflet with white background and black text, giving directions for taking the painkiller Ibuprofen + Codeine.

IMG Source: chemist-4-u.com

Combining Nurofen and Paracetamol Safely

  • Nurofen (Ibuprofen): Nurofen, a brand name for ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID) that aids in reducing pain, swelling, and fever.
  • Paracetamol (Acetaminophen): Paracetamol is a common pain reliever known for its safety in treating mild to moderate pain and fever.
  • Taking Both Together: It is safe to combine Nurofen (ibuprofen) with paracetamol for effective pain relief. Always adhere to dosage instructions to avoid surpassing recommended limits for each medication.
  • Who Should Be Cautious: Individuals with specific health conditions such as allergies to NSAIDs, stomach ulcers, heart failure, liver disease, kidney problems, or lupus, among others, need to be cautious. Pregnant women may find paracetamol a safer option during pregnancy.

Remember, seek advice from a healthcare professional tailored to your unique health circumstances for personalized recommendations.


A box of Nurofen tablets on a wooden table.

IMG Source: medicalprices.co.uk

In conclusion, the question ‘Can I take Nurofen Plus and paracetamol together?’ is commonly asked by individuals seeking relief from pain. While combining these medications can provide effective pain management, it is essential to follow safety precautions and dosage guidelines. Always consult a healthcare professional before taking any medication, especially when considering combining Nurofen Plus and paracetamol.

Your health and well-being should always be the top priority. Remember, proper dosing and understanding potential interactions are crucial for your safety and overall health. Stay informed, stay safe!


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