Enoxaparin 80 mg 0.8 ml Syringe: Dosage and Administration

Understanding Enoxaparin 80 mg 0.8 ml Syringe

When it comes to administering enoxaparin sodium, a crucial anticoagulant medication used in haemodialysis to prevent thrombus formation, proper preparation and dosage are paramount. One specific form is the enoxaparin 80 mg 0.8 ml syringe, which necessitates precise dilution with normal saline or dextrose solution for safe and effective use. Understanding the meticulous steps involved in preparing and administering this medication is vital to ensure optimal patient care and outcomes.

Administering Enoxaparin Sodium Safely and Effectively

When it comes to administering enoxaparin sodium, a common anticoagulant medication used in the prevention of thrombus formation during haemodialysis, there are specific guidelines that need to be followed to ensure safe and effective treatment. One such preparation is the enoxaparin 80 mg 0.8 ml syringe, which requires careful dilution with normal saline solution (0.9%) or 5% dextrose in water before administration.

To prepare this medication for injection, a healthcare professional must first withdraw 30 mL from an infusion bag using a syringe and discard the liquid. Next, they inject the complete contents of a 6,000 IU (60 mg) enoxaparin sodium pre-filled syringe into the remaining 20 mL in the bag, gently mixing the contents to ensure proper dilution. The volume of diluted solution can then be calculated using a formula or by referencing a table provided.

For instance, if a patient weighs 70 kg, the required dose would be 21 IU (0.21 mg) per kilogram, which translates to 14.7 mL when diluted to a final concentration of 300 IU (3 mg)/mL. This calculation is crucial to ensure that the patient receives the correct dosage, as enoxaparin sodium is a potent anticoagulant.

In addition to proper dilution and dosing, there are specific guidelines for switching between enoxaparin sodium and oral anticoagulants or direct oral anticoagulants (DOACs). When transitioning from one medication to another, it’s essential to monitor the patient’s response and adjust dosages accordingly. Furthermore, when administering enoxaparin sodium in spinal/epidural anaesthesia or lumbar puncture, careful neurological monitoring is recommended due to the risk of neuraxial haematomas.

Important Considerations

  • Puncture-free interval: A minimum of 12 hours should be kept between the last injection of enoxaparin sodium and needle or catheter placement for prophylactic doses.
  • Dosage adjustment: Patients with creatinine clearance of 15-30 mL/min may require doubling the timing of puncture/catheter placement or removal.

By following these guidelines and taking into account individual patient factors, healthcare professionals can ensure safe and effective use of enoxaparin sodium, including the enoxaparin 80 mg 0.8 ml syringe.

In conclusion, the meticulous preparation and administration of enoxaparin sodium, especially in the form of the enoxaparin 80 mg 0.8 ml syringe, require careful attention to detail and adherence to specific guidelines. Healthcare professionals must calculate dosages accurately, dilute the medication correctly, and monitor patients closely for any potential adverse effects or interactions. By following these protocols diligently, healthcare providers can ensure the safe and effective use of enoxaparin sodium, promoting better treatment outcomes for patients in need of anticoagulation therapy.


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