Who Makes Ibuprofen: Manufacturers and Production Overview

Who Makes Ibuprofen: Key Manufacturers, Production Process, and Future Outlook

Welcome to the fascinating world of ibuprofen, a revolutionary compound that has transformed pain management and healthcare practices globally. Discover the intriguing journey of ibuprofen, from its serendipitous discovery in the 1960s to becoming a staple in medicine cabinets worldwide. Learn about the key players who make ibuprofen possible and the significant impact it has on healthcare and the economy.

Discovery and Impact of Ibuprofen

  • Discovery and Development: In the 1960s, English research scientist Stewart Adams and John Nicholson discovered ibuprofen while searching for a cure for rheumatoid arthritis. This compound marked a significant advancement in pain management, becoming a popular NSAID for pain, fever, and inflammation.
  • From Prescription to Over-the-Counter: Ibuprofen was patented in 1961 and approved for use in 1969. By 1983, it transitioned to being widely available over the counter, with brands like Brufen, Advil, and Motrin making it accessible globally.
  • Idioms and Impact: Ibuprofen rapidly gained popularity, with phrases like “hitting the shelves” reflecting its journey from the lab to global sensation.

    Today, one package of ibuprofen is sold every three seconds in the United States.

Stewart Adams tested ibuprofen on his hangover, leading to its breakthrough use. His perseverance has benefited millions worldwide, ushering in a headache-free world. Cheers to science and relief!


A black and white portrait of a man with a background of red pills.

IMG Source: cdn-si-edu.com

Key Players in Ibuprofen Production

Here are some key players in the world of ibuprofen production: BASF SE, a major player in the pharma industry involved in producing ibuprofen meeting USP and EP standards. Perrigo Company PLC plays a significant role in making ibuprofen available in various forms. Shandong Xinhua Pharmaceutical Co., Ltd.

is a notable Chinese producer of ibuprofen, meeting a significant portion of the U.S.’s requirements. SI Group, Inc. contributes to ibuprofen production for pain management purposes.

Strides Pharma Science Limited engages in manufacturing and distributing ibuprofen globally. IOL Chemicals & Pharmaceuticals Ltd. actively produces ibuprofen to cater to global needs.

A technology-focused market overview, including market size, CAGR value, segmentation, key players, industry developments, and regional analysis.

IMG Source: licdn.com

FDA Regulations and Compounding Guidance

  • Food and Drug Administration (FDA) Regulations:
    • – The FDA sets guidelines and regulations for the production and quality control of ibuprofen, an NSAID.
    • – The FDA’s draft guidance on Ibuprofen provides recommendations for bioequivalence studies to support generic versions of the medication.
    • – Quality control personnel under 21 CFR part 111 must ensure dietary supplements meet specified standards.
  • Compounding Guidance:
    • – The FDA issued guidance on compounding ibuprofen oral suspension products in outsourcing facilities for use in hospitals and health systems.

A graphic explaining how to optimize ibuprofen and acetaminophen fixed-dose combination tablets.

IMG Source: basf.com

Healthcare and Economic Impact of Ibuprofen

  • Healthcare Impact:
    • Pain Management: Ibuprofen is a widely used nonsteroidal anti-inflammatory drug that provides relief for arthritis, bone fractures, muscle pains, headaches, dental pain, and acute pain from injury or surgery.
    • Fever Reduction: It is also effective in reducing fever and alleviating common cold or flu symptoms.
    • Pediatric Use: Children benefit from ibuprofen for treating fever, sore throat, and minor ailments.
    • Rapid Results: Ibuprofen offers fast relief and targeted drug delivery.
    • Prevalence of Pain-Related Issues: Chronic pain is on the rise globally with millions suffering daily in countries like the U.K. and the U.S.
    • Cancer and Cardiovascular Diseases: Conditions like cancer, cardiovascular diseases, back pain, and trauma drive the demand for ibuprofen in pain management.
  • Economic Impact:
    • Market Size: The global ibuprofen market is projected to reach USD 687.77 million by 2023, with a CAGR of 2.1%. Manufacturing ibuprofen as an active pharmaceutical ingredient fuels this market for NSAID medications.
    • Urbanization and Sales: Market growth is driven by increased healthcare spending, urbanization, and escalating sales of analgesic drugs.
    • Challenges: Factors like adverse side effects and fluctuating raw material prices pose challenges to the industry.

Ibuprofen’s production has a significant impact on both healthcare and the economy, influencing pain management practices and market dynamics worldwide.

A chart shows the share of the ibuprofen API market by end-user, with pharmaceutical companies and contract manufacturing organizations as the two end-users.

IMG Source: technavio.com

In conclusion, the production of ibuprofen plays a vital role in providing relief from pain, fever, and inflammation to millions around the world. The key players involved in making ibuprofen, such as BASF SE, Perrigo Company PLC, and Shandong Xinhua Pharmaceutical Co., Ltd., ensure that this essential medication meets the highest standards of quality and efficacy. As the global demand for ibuprofen continues to rise, it highlights the importance of this NSAID in healthcare.

By understanding the regulations, healthcare impact, and economic influences of ibuprofen production, we can appreciate the intricate processes that go into making this widely used medication. So, next time you reach for that ibuprofen bottle, remember the dedication and innovation behind its production. Who makes ibuprofen?

These companies and their commitment to excellence ensure that relief is just a pill away.


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