Guides
Canfora
No, you shouldn’t take Nurofen (ibuprofen) and Voltaren tablets (diclofenac) together. They are both anti-inflammatories (NSAIDs) that work the same way, so combining them doubles the risk of stomach bleeding and kidney problems without adding much relief. Voltaren gel on one joint is a different matter, and paracetamol combines well with either.

The short answer
They are different medicines from the same family. Nurofen contains ibuprofen; Voltaren contains diclofenac. Both are non-steroidal anti-inflammatory drugs (NSAIDs) that block the COX enzymes making prostaglandins. That shared mechanism is why they shouldn’t be taken together: the side effects (stomach irritation, kidney strain, raised blood pressure, bleeding) add up, while the pain relief does not double.
| Nurofen | Voltaren | |
|---|---|---|
| Active ingredient | Ibuprofen | Diclofenac (potassium in Voltaren Rapid; sodium in enteric-coated tablets) |
| Typical OTC tablets | 200–400 mg | 12.5–25 mg (Voltaren Rapid 12.5 and 25) |
| Prescription doses | Up to 2,400 mg/day | 75–150 mg/day |
| Gel | Nurofen Gel 5% | Voltaren Emulgel 1% and 2% |
| Heart and stroke risk | Lower at OTC doses | Higher; regulators restricted its use in heart disease in 2013 |
Every NSAID, at its full dose, already blocks prostaglandins nearly as much as it usefully can. Adding a second NSAID mostly adds side effects: indigestion, stomach ulcers and bleeding; less blood flow to the kidneys (dangerous when dehydrated or on blood pressure medicines); fluid retention and higher blood pressure. The same rule applies to naproxen (Naprogesic, Aleve), aspirin at pain-relief doses, mefenamic acid (Ponstan), meloxicam and celecoxib: one at a time.
Switching between them: if you’ve taken Nurofen and want to switch to Voltaren, wait until the next Nurofen dose would have been due (about 6–8 hours) before taking diclofenac, and don’t go back and forth during the same day.
Diclofenac gel rubbed on a knee or hand reaches blood levels of only a few per cent of those from tablets. That’s why gels are recommended for older people and for osteoarthritis of the knee and hand. Even so, product leaflets ask you to check with a pharmacist before using the gel with oral NSAIDs, especially if you use large amounts or several areas. A sensible approach is:
| Combination | Verdict |
|---|---|
| Nurofen + Panadol | Fine for most adults; see Nurofen and Panadol together |
| Voltaren Rapid + Panadol | Fine for most adults |
| Voltaren gel + Panadol | Fine |
| Nurofen + Voltaren tablets | Avoid |
| Nurofen + naproxen (Naprogesic, Aleve) | Avoid |
| Nurofen + Ponstan (mefenamic acid) | Avoid |
| Maxigesic (ibuprofen + paracetamol) + Voltaren | Avoid: Maxigesic already contains an NSAID |
Which painkiller suits which pain is set out in the pain relief guide.
No. Naproxen and ibuprofen are both NSAIDs. Take one or the other, and add paracetamol if you need more relief.
No. Mefenamic acid (Ponstan) is also an NSAID. Choose one; paracetamol or a heat pack can be added.
Panadol for headaches, fever and general aches, especially if you have stomach, kidney or heart concerns. Nurofen for inflammatory pain such as period pain, toothache or sprains. Voltaren tablets are an alternative to Nurofen for musculoskeletal pain, but they have a higher heart risk; many pharmacists prefer ibuprofen or diclofenac gel.
A single overlap is unlikely to cause harm in a healthy adult. Don’t take more of either for the rest of the day, take paracetamol if you need more relief, and eat something. Seek advice if you develop stomach pain, black stools or vomiting.
More on this topic: every common painkiller and which ones combine are covered in Pain Relief Guide: Paracetamol, Ibuprofen, Aspirin and More.
Medical disclaimer: this article is general information, not a diagnosis or a personal recommendation. Check with your doctor or pharmacist before starting, stopping or combining medicines. Read the full disclaimer.